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October 2022

Afr J Med Med Sci. 1988 Dec; 17(4): 227-30.

Screening extracts of Euphorbia garuana N.E.Br. for in-vitro cytotoxicity.

Abo KA.

Department of Pharmacognosy, Faculty of Pharmacy, College of Medicine, University of Ibadan, Nigeria.

Two biological assays utilising in-vitro uptake of 3H-thymidine into TLX/5 lymphoma and rat basophilic leukaemia cells have been used for rapid detection and subsequent isolation of active compounds from the latex of Euphorbia garuana (Euphorbiaceae). Two potent esters were characterized from the latex of E. garuana reportedly used in traditional medicine for the treatment of certain forms of cancer.

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