Int Arch Allergy Appl Immunol. 1986 ; 80(3): 253-7.

Human IgG antibody responses to grass pollen antigens: effects of immunotherapy and comparison of serum and secretory profiles.

Deards MJ, Standring R, Moran DM.

IgG antibody responses, induced by individual temperate grass pollen allergens in atopic subjects, have been studied by an SDS-PAGE immunoprecipitation technique. These were shown to be of a complex nature and variable between individuals. Profiles obtained with serum and nasal secretions from the same individual were qualitatively similar. Immunotherapy with a glutaraldehyde-modified grass pollen extract, Pollinex, increased the level of specific IgG to three clinically significant grass pollen allergens but did not markedly change the overall pattern of response.