Nachweis und quantitative Bestimmung von Lektinen und Viscotoxinen in Mistelpräparaten

Journal/Book: Arzneim.- Forsch./ Drug Res. 36 (3), 428-433. 1986;

Abstract: Mistletoe lectins and viscotoxins, which up to now have been isolatedonly from plant material, were detected and quantitatively determined inthe mistletoe preparation Iscador(Reg.trademark) and in a fermentedmistletoe extract. Lectins were isolated by affinity chromatography andanalyzed by isoelectric focussing. Thus, in Iscador and in the fermentedmistletoe extract only the mistletoe lectins ML II/III were foundwhereas typical proteins of the ML I complex were missing. The lectincontent of the preparation and the extract was determined by 'singleradial immunodiffusion' (SRID). For identification and quantitativedetermination of viscotoxins, a HPLC method was designed.COPYRIGHT BY Elsevier Science BV, Amsterdam, Netherlands END OF DOCUMENT

Keyword(s): lectin

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