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November 2022

Stellenwert des Lymphozytentransformationstests für die Bestimmung des Immunstatus

Journal/Book: Dermatologica 171 (3), 158-162. 1985;

Abstract: Studies on lymphocyte stimulation in vitro were carried out with variousperspectives. Apart from the well-known mitogens such as PHA and ConA,Candida extract and mercury ions had a relatively strong stimulatoryeffect, mistletoe extract a moderate one, nickel ions and trichophytinnone at all. In malignant lymphomas the degree of stimulation wasgreatly reduced. In malignant melanomas the degree of stimulation, whichat the beginning was often quite low, increased during the course oftreatment. There was no correlation between the response to recallantigens and the degree of lymphocyte stimulation. The lymphocytestimulation test did not prove reliable for the detection of drugallergies. Author.


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