Über die medikamentöse Beeinflussung zellulärer Resistenzmechanismen im Tierversuch. Aktivierung von Peritonealmakrophagen der Maus

Journal/Book: Arzneim-Forsch/Drug Res. 1982; 2:

Abstract: On the Influence of Drugs on Cellular Mecha-nisms of Resistance in the Animal Experiment / Activation of peritoneal macrophages of the mouse by a resistance stimulant on plant base.Enzyme activity of Iysosomal hydrolases and phagocytosis of Staphylococcus aureus were investigated in peritoneal macrophages of mice. After the in vivo stimulation by a single treatment with thioglycolate broth or a host-resistance stimulant on plant base (Esberitox.) the elicited peritoneal macrophage population exhibited characteristics of activation. These non specifically activated macrophages secreted higher amounts of Iysosomal enzymes and demonstrated a higher phagocytotic activity than resident macrophages.

Keyword(s): Esberitox

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Über die medikamentöse Beeinflussung zellulärer Resistenzmechanismen im Tierversuch. Aktivierung von Peritonealmakrophagen der Maus - pflanzliche Reizkörper