Mineralokortikoidale Aktivität bei serieller Hyperthermie

Author(s): Jungmann, E., Bachhaus, Kirn, R., Pirlet, K.

Journal/Book: Z Phys Med Baln Med Klim. 1982; 11: 331-341.

Abstract: 10 male volunteers have been immersed in a standardized hyperthermic water bath on 10 (n = 6, Trectal = + 1,51°C) and on 9 (n = 4, Trectal = + 1,15°C) consecutive days for 75 minutes. During these series sweat excretion increased from 660 to 9819 (n = 6) and from 437 to 646 9 (n = 4). Na-concentration in a probe from the front as well as diuretic and natriuretic reaction decreased significantly in the same time. Urinary excretion of aldosterone was not changed.These parameters of an increased mineralocorticoidal activity with a sign of identical plasma concentration of biological active aldosterone are explained by a higher density of hormone specific receptors within the target cells after a thermal adaption.

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