Biull Eksp Biol Med. 1981 Oct; 91(10): 440-2.

[Effect of motropin and naloxone on electroacupuncture analgesia]

Zakusov VV, Iasnetsov VV, KaliuzhnyÄ LV, Golanov EV.

It was demonstrated in experiments on awake rabbits that electroacupuncture increases the pain threshold (the tail-flick-test) and suppresses the second positive wave of evoked potential in the somatosensory cortex in response to nociceptive electrocutaneous stimulation. Naloxone, the typical antagonist of narcotic analgetics, in doses of 0.05-0.1 mg/kg completely blocks the effects induced by electroacupuncture. The similar effects were produced by motropin, a new antagonist of narcotic analgetics, belonging to the tropan series, administered in doses of 10-20 mg/kg.