Isolation and properties of three lectins from mistletoe (VISCUM ALBUM L.)

Journal/Book: Biochem. J. 195, 481-484. 1981;

Abstract: Three lectins have been isolated from an extract of mistletoe (Viscumalbum) by affinity chromatography on partially hydrolysed Sepharose andhuman immunoglobulin- Sepharose. The lectins differ in molecular weightand sugar specificity (lectin I, mol.wt. 11500, D-galactose-specific;lectin II, mol.wt. 60000, both D-galactose- andN-acetyl-D-galactosamine-specific; lectin III, mol. wt. 50000,N-acetyl-D-galactosamine-specific). All three lectins react with humanerythrocytes without specificity for the A, B, and O blood groups. Incontrast with abrin and ricin the mistletoe lectins cannot be dividedinto "toxins" and "haemagglutinins". Author.

Keyword(s): CARBOHYDRATES/PD (pharmacology)

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