Elektronystagmographisch und klinisch dokumentierte Therapieerfahrungen mit rökan bei Schwindelsymptomatik

Journal/Book: Therapiewoche. 1981; 31: 8658-8667.

Abstract: In a specialist's practice possessing the relevant apparatus and experience, 50 patients (17 males and 33 females, average age 43 yrs) with symptoms of dizziness were first of all treated for two months with rökan® in open trial (3 times 1 coated tablet/dragee per diem), and after this for a further two months either with placebo or rökan 1/2 in a double-blind procedure. All patients were subjected to a thorough neurootological examination before therapy, after two months and after four months; in each case especially, electronystagmograms were recorded with carorimetry and the rotary chair examination, and evaluated according to Claussen in the butterfly or the L pattern. After these results, with simultaneous subjective progress check, the treatment results were classified as very good, good, moderate or failure. In total, 66% of the results obtained were "very good" and "good" after two months of rökan treatment. Particularly good reactions were obtained in cases of dizziness symptoms in conjunction with demonstrated C.V.C. syndrome, and those with peripheral circulatory insufficiency of the inner ear. After long-term treatment (4 months), the results were improved to an even greater extent: a considerable percentage of the results previously classified as "good" could, at the end of the trial, be evaluated as "very good". On the other hand, more than half of the cases receiving placebo became worse, nearly all of those initially classified as "good" and "very good" were reversed. Tolerance of the active drug was excellent during the entire treatment period; under placebo administration, two patients complained of mild side-effects. According to our experience with this patient group, a therapy trial with rökan® can be recommended for all patients with dizziness symptoms, independent of age and duration of the disease.

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