Cancer Lett. 1979 Nov; 8(1): 87-92.

Mutagenicity of chamuvaritin: a benzyldihydrochalcone isolated from a medicinal plant.

Uwaifo AO, Okorie DA, Bababunmi EA.

The mutagenic effects of chamuvaritin, dihydrobenzylchalcone isolated from Uvaria chamae, were investigated using Salmonella typhimurium tester strains TA92, TA94--98, TA100--1535, TA1537 and TA1538. The phytochemical was mutagenic in tester strains TA98 and TA100 and required activation by the hepatic S-9 microsomal enzyme preparation.