Some observations on the mechanism of fobrinolytic enhancing effect of garlic during alimentary lipaemia in me

Author(s): Sharma, S., Arora, R.

Journal/Book: Journal of Postgraduate Medicine. 1978; 24: 98-102.

Abstract: An increase in plasma cholesterol and fibrinogen and a decrease in blood fibrinolytic activity (BFA) was observed during alimentary lipaemia produced by an ingestion of a; fatty breakfast by healthy volunteers. Addition of garlic in its both raw and boiled forms to fatty break fast was found to prevent the rise in cholesterol end fibrinogen in blood and to produce an enhancement of BFA. Fibrinolytic enhancing effect of garlic seems to be mediated through an increase in blood activator of fibrinolysis. A decrease in blood cholesterol may also contribute to this action indirectly as increased concentration of this lipid was found to decrease the BFA.

Keyword(s): Allium sativum

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