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December 2024

Electrolyte and Lipid Metabolism of Lean Fasting Men and Women

Journal/Book: Metabolism 15: No. 5 May 401-408 1966. 1966;

Abstract: WALTER LYON BLOOM M.D.: Director of Medical Education - Research Piedmont Hospital Atlanta Ga.; Clinical Associate Medical College of Georgia Augusta Ga.; GORDON AZAR M.D.: Resident in Medicine Piedmont Hospital Atlanta Ga.; JAMES E. CLARK M.D.: Assistant Resident in Medicine Piedmont Hospital Atlanta Ga.From the Ferst Research Center of Piedmont Hospital Atlanta Georgia. Supported by United States Public Health Service grant HE 05301-05. Received for publication Feb. 9 1966. Total plasma lipid cholesterol and free fatty acid was measured during a 4 day fast of 7 lean men and 7 lean women. Urinary excretion of sodium potassium and creatinine was measured. All parameters of fat metabolism increased more rapidly in women when rate of fasting is defined by negative caloric balance rather than time. No sex difference was found in sodium or potassium excretion. The potassium to creatinine ratio was lower in lean fasting men than women. T HE REASON for correlating the energy balance as well as sex with the metabolic changes of fasting has been demonstrated.1 It was shown that fasting should be defined by quantitation of total negative caloric balance rather than time alone. Ketone nitrogen and energy balance was presented. While these studies were performed it was possible to observe the changes in electrolytes and blood lipids in fasting lean men and women... schö


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