REGIONAL PULMONARY FUNCTION STUDIED WITH XENON133 * SO/ Journal of Clinical Investigation Val. 41 No. 3 1962

Abstract: BY W. C. BALL JR. Â† P. B. STEWART L. G. S. NEWSHAM AND D. V. BATES From the Joint Cardiorespiratory Service and Department of Radiology Royal Victoria Hospital McGill University Montreal Canada (Submitted for publication August 15 1961; accepted November 9 1961) *Presented in part at the Forty-fifth Annual Meeting of the Federation of American Societies for Experimental Biology Atlantic City N. J. April 14 1961 (1). The equipment used in this study was largely paid for by a Dominion Provincial Grant. The investigative work has been supported by a Block Term Grant from the Medical Research Council of Canada and during the past year by generous support from the John A. Hartford Foundation. Â† Postdoctoral Research Fellow of the National Heart Institute. Present address : Department of Medicine The Johns Hopkins Hospital Baltimore 5 Md. SUMMARY AND CONCLUSIONS 1. A radioactive isotope of the inert gas xenon has been used in conjunction with externally placed scintillation counters to estimate separately the function of six different regions of the lung. By comparison of external counting rates after a single breath and after rebreathing an air-xenon mixture it has been possible to compute an Index of relative ventilation that is independent of the volume of lung ... schö

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