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October 2021

THE PULMONARY PHYSIOLOGY OF NORMAL INDIVIDUALS LIVING AT AN ALTITUDE OF ONE MILE1

Journal/Book: Reprinted from THE JOURNAL OF CLINICAL INVESTIGATION VOI. XXXII NO. 6 pp. 490-496 June 1953. 1953;

Abstract: From the Cardiovascular Pulmonary Laboratory Department of Medicine University of Colorado School of Medicine Denver Colo. Submitted for publication January 27 1953; accepted February 25 1953 1 This study was supported by a gram (H-241) from the United States Public Health Service with additional Support provided by a grant (CTAE-100) from the National Foundation for Infantile Paralysis Inc. SUMMARY There are few known studies of pulmonary function of normal acclimated individuals living at a median altitude (1 mile). Therefore the establishment of "normal" values for the various tests used in measuring pulmonary function was undertaken. Furthermore the establishment of the effect of this median altitude upon the results of the tests is necessary to Interpret them properly. Unfortunately few studies of pulmonary function have been done in a similar manner at sea level with which to compare these results. A significant increase in resting minute ventilation is established for this altitude of one mile and minute ventilation is increased during exercise. The increase in ventilation lowers carbon dioxide content and tension in the peripheral arterial blood below values obtained at sea level. ___MH


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