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May 2024

Planta Med. 2003 May; 69(5): 434-9.

Diterpenoid and phenolic glycosides from the roots of Rhododendron molle.

Bao GH, Wang LQ, Cheng KF, Feng YH, Li XY, Qin GW.

Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, P. R. China.

Two new grayanane diterpenoid glucosides, rhodomosides A (1), B (2) and two new phenolic glycosides 3, 4 together with a known glucosyringic acid (5) were isolated from the roots of Rhododendron molle G. Don (Ericaceae). Their structures were elucidated on the basis of spectral analysis. Compounds 3, 4 and 5 were found to inhibit the proliferation of murine B lymphocytes in vitro, while compound 3 also showed stimulatory activity on the proliferation of murine T lymphocytes in vitro.


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