Fitoterapia. 2003 Apr; 74(3): 302-4.

Preliminary evaluation of inhibition of matrix-metalloprotease MMP-2 and MMP-9 by Passiflora edulis and P foetida aqueous extracts.

Puricelli L, Dell'Aica I, Sartor L, Garbisa S, Caniato R.

Dipartimento di Biologia, V le G Colombo 3, Padova 35131, Italy.

Fruit's decoctions of Passiflora edulis and P. foetida var. albiflora were evaluated for the inhibition of activity of gelatinase MMP-2 and MMP-9, two metallo-proteases involved in the tumour invasion, metastasis and angiogenesis. Both water extracts, at different concentrations, inhibited the enzymes.