Fitoterapia. 2003 Apr; 74(3): 274-9.

Antihyperglycemic activity of Caralluma attenuata.

Venkatesh S, Reddy GD, Reddy BM, Ramesh M, Rao AV.

G Pulla Reddy College of Pharmacy, Mehdipatnam, Hyderabad 500 028, India. venkateshsama@hotmail.com

Extracts of Caralluma attenuata are screened for their antihyperglycemic activity. Ethanol, chloroform and butanol extracts were tested on glucose loaded and alloxan-induced diabetic rats. In both tests, the butanol extract, at the oral dose of 250 mg/kg, has shown statistically significant and considerable antihyperglycemic activity.