J Am Acad Dermatol. 2003 Apr; 48(4): 628-30.

Nonpigmenting solitary fixed drug eruption caused by a Chinese traditional herbal medicine, ma huang (Ephedra Hebra), mainly containing pseudoephedrine and ephedrine.

Matsumoto K, Mikoshiba H, Saida T.

Department of Dermatology, Shinshu University School of Medicine, Matsumoto, Japan. dermatsu@hsp.md.shinshu-u.ac.jp

We describe a case of nonpigmenting solitary fixed drug eruption appearing on the right thigh of a 31-year-old woman in Japan. The causative drug was determined by closed patch test on postlesional skin as a Chinese traditional herbal medicine, ma huang (Ephedra Hebra), mainly containing pseudoephedrine and ephedrine.