Dent Clin North Am. 2002 Oct; 46(4): 857-68.

Oral manifestations of drug therapy.

Guggenheimer J.

Departments of Oral Medicine, Pathology, and Otolaryngology, University of Pittsburgh School of Dental Medicine, 3501 Terrace Street, G-137 Salk, Pittsburgh, PA 15261, USA. guggen@pitt.edu

The oral cavity may be the target organ for a number of diverse abnormalities that develop from side effects of medications. Because of the widespread and increasing use of prescription, over-the-counter, and herbal remedies, it is becoming increasingly likely that the dentist will encounter soft tissue or dental pathologies that represent a complication of a therapeutic agent. The more common abnormalities that may occur include gingival hyperplasia, tooth discoloration, candidiasis, chemical injuries, and altered taste perception. The dental practitioner is often the primary health care provider who can recognize, diagnose, treat, and/or prevent these conditions.