Phytother Res. 2002 Nov; 16(7): 696-9.

Psychopharmacological profiles of Leucas Lavandulaefolia Rees.

Mukherjee K, Saha BP, Mukherjee PK.

Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University, Calcutta - 700032, India. mukherjeepk@rediffmail.com

Methanol extract of Leucas lavandulaefolia (LLFE) was evaluated for different psychopharmacological profiles with various animal models in rats and mice. The extract showed a potential reduction in spontaneous activity and caused a significant decrease in exploratory behavioural pattern by the head dip and Y-maze test. It also showed a significant reduction in muscle relaxant activity by rotarod, 30 degrees inclined screen and traction tests. The extract showed a remarkable potentiation of pentobarbitone induced sleeping time in mice.Copyright 2002 John Wiley & Sons, Ltd.