Fitoterapia. 2002 Oct; 73(6): 517-9.

Preliminary evaluation of Kielmeyera coriacea leaves extract on the central nervous system.

Audi EA, Otobone F, Martins JV, Cortez DA.

Department of Pharmacy and Pharmacology, Universidade Estadual de MaringÃ¡, PR, Brazil. eaaudi@uem.br

The hydroalcoholic extract of Kielmeyera coriacea leaves was evaluated for effects on the central nervous system by means of behavioral models which included forced swimming, open-field and elevated plus-maze tests. According to the results, K. coriacea leaves extract is effective as anxiolytic but not as an antidepressant drug.Copyright 2002 Elsevier Science B.V.