Wien Med Wochenschr. 2002 ; 152(15-16): 393-7.

[Pharmacodynamic effects and clinical effectiveness of a combination of herbal substances comprised of Cone Flower, Wild Indigo and White Cedar]

KÃƒÂ¶hler G, Bodinet C, Freudenstein J.

Medizinischen Forschung von Schaper & Brümmer GmbH & Co. KG, Bahnhofstrasse 35, D-38259 Salzgitter, Deutschland. gert.koehler@schaper-bruemmer.de

The effect of the single active ingredients Echinaceae (purpureae et pallidae) radix, Baptisiae tinctoriae radix and Thujae occidentalis herba as well as of the combination Esberitox N has been verified in vitro, in vivo, in animal experiments and in human pharmacology (5). The pharmaceutical has immunomodulating and antiviral characteristics, whereby the immune system is probably influenced unspecifically, especially by increasing the macrophage activity. The efficacy for viral respiratory tract infections has been proven yet again in recent GCP-compliant, clinical studies (15, 17). Under the influence of the phytotherapeutic the duration of the illness decreased with a responder rate that was significantly higher than under placebo. The therapeutic benefit was even more pronounced, if the pharmaceutical was applied as early as possible. It has a high drug safety.