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May 2024

J Asian Nat Prod Res. 2002 Sep; 4(3): 227-31.

Three new phlegmariurine B type lycopodium alkaloids from Huperzia serrata.

Tan CH, Chen GF, Ma XQ, Jiang SH, Zhu DY.

State Key Laboratory of New Drug Research, Shanghai Institute of Material Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences.

Phlegmariurine B (1), a known alkaloid, along with three new analogous compounds, 2alpha-hydroxyphlegmariurine B (2), 2-oxoyphlegmariurine B (3) and 11-oxophlegmariurine B (4), were isolated from the CHCl3 fraction of total alkaloids of whole plant of the Chinese medicinal herb Huperzia serrata. Their structures were elucidated by spectral analysis.


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