J Ethnopharmacol. 2002 Jun; 81(1): 43-7.

Evaluation of the antinflammatory and analgesic activity of Sideritis canariensis var. pannosa in mice.

HernÃ¡ndez-PÃ©rez M, Rabanal RM.

Departamento de EnfermerÃa, E.U. de EnfermerÃa y Fisioterapia, Universidad de La Laguna, C/Campus de Ofra, s/n, 38071, La Laguna, Tenerife, Spain. maherpe@ull.es

A previous chemical study of Sideritis canariensis var. pannosa demonstrated the presence of some important classes of related organic compounds with anti-inflammatory activities. In the present study, the crude ethanol extract and the chloroformic and aqueous fractions of S. canariensis have been examined for their antimicrobial actions through the disk-diffusion method and for their anti-inflammatory and analgesic effects in several animal models. No relevant antimicrobial activity against the tested microorganisms was found. The chloroformic fraction was the most interesting, exhibiting a good analgesic and anti-inflammatory activity.