Fitoterapia. 2002 Apr; 73(2): 111-5.

Preliminary study on antifertility activity of Calotropis procera roots in female rats.

Kamath JV, Rana AC.

Department of Pharmacology, Krupanidhi College of Pharmacy, Sarjapur Road, Kormanagala, Bangalore 560 034, India. jvkam@rediffmail.com

The effect of ethanolic extract of the roots of Calotropis procera has been studied in albino rats to explore its antifertility and hormonal activities. A strong antiimplantation (inhibition 100%) and uterotropic activity was observed at the dose level of 250 mg/kg (1/4 of LD(50)). No antiestrogenic activity could be detected.