Zhong Yao Cai. 2001 Oct; 24(10): 739-40.

[Study on the protective effect of xinkang oral liquid on the isoproterenol-induced ischemic myocardial damage in rats]

He X, Cui J, Li Y.

107th Center Hospital of PLA, Yantai 264002.

OBJECTIVE: To study the protective effect of Xinkang oral liquid on the ischemic myocardial damage. METHODS: Ischemic myocardial damage model was obtained by i.p. 85 mg/kg isoproterenol. The level of superoxide dismutase (SOD), malondialdehyde (MDA), creatine kinase (CK), lactic dehydrogenase (LDH) in the serum and endothelin (ET) in the plasma were detected. RESULTS: The level of ET, MDA, CK, LDH of Xinkang oral liquid group was much lower than that of model group (P < 0.01). The SOD activity was higher than that of model group (P < 0.01). The level of Xinkang oral liquid group was lower than that of Shuxin oral liquid group. The SOD activity of Xinkang oral liquid group was much higher than that of Shuxin oral liquid group (P < 0.01). CONCLUSION: Xinkang oral liquid can prevent the myocardium from ischemic damage.