Fitoterapia. 2001 Aug; 72(6): 680-5.

Cytotoxicity screening of some South American Solanaceae.

Moreno-Murillo B, Fajardo VM, SuÃ¡rez M.

Departamento de QuÃmica, Facultad de Ciencias, Universidad Nacional de Colombia, A.A. 27586, BogotÃ¡, DC 1, Colombia.

Alcoholic extracts of seven plants belonging to the Solanaceae family were phytochemically screened and evaluated for their cytotoxic activity by Brine Shrimp Test (BST) with Artemia salina larvae, Inhibition of Cell Division Test (ICDT) on sea urchin Loxechinus albus fertilized eggs and inhibition of crown gall tumors on Potato Disk Bioassay (PDB). From Salpichroa diffusa, bioassay-guided chromatographic separation afforded some active fractions from which epi-katonic acid was identified.