J Neuropsychiatry Clin Neurosci. 2000 Spring; 12(2): 177-92.

The use of herbal alternative medicines in neuropsychiatry. A report of the ANPA Committee on Research.

LaFrance WC, Lauterbach EC, Coffey CE, Salloway SP, Kaufer DI, Reeve A, Royall DR, Aylward E, Rummans TA, Lovell MR.

Department of Neurology, Brown University School of Medicine, Rhode Island Hospital, Providence 02903, USA. clafrance@pol.net

Growing numbers of people throughout the United States (40% in 1998) are using various forms of alternative therapies. A MEDLINE literature search of journals from the past three decades and an Internet database query were performed to determine the types and frequency of alternative therapies used, with special attention given to the herbal medicines used in neuropsychiatric disorders. Clinical effects, mechanisms of action, interactions, and adverse reactions of the herbal treatments are detailed. Objective controlled trials will be needed to establish safety and efficacy of herbal supplements. Knowledge of the properties of these therapies can improve the care of neuropsychiatric patients.