Fitoterapia. 2000 Aug; 71 Suppl 1(): S138-40.

Antimicrobial activity of crude extracts and pure compounds of Hypericum hircinum.

Pistelli L, Bertoli A, Zucconelli S, Morelli I, Panizzi L, Menichini F.

Dipartimento di Chimica Bioorganica e Biofarmacia, UniversitÃ di Pisa, via Bonanno 33, 56126 Pisa, Italy. luipi@farm.unipi.it

The antimicrobial activity of the n-hexane (H) and chloroform (C) extracts, the methanol extract (M) and its ethyl acetate (E) and n-butanol (B) fractions, and six isolated constituents of the aerial parts of Hypericum hircinum was investigated using an agar diffusion method. The maximum activity was exhibited by the methanolic extract against Staphylococcus aureus, while all pure constituents showed no antimicrobial activity against the tested microorganisms.