Delayed recognition memory in Parkinson's disease: a role for working memory?

Author(s): Gabrieli, J. D. E., Masciari, F., Monti, L., Goetz, C. G.

Journal/Book: Neuropsychologia. 1999; 37: the Boulevard Langford Lane, Kidlington, Oxford Ox5 1GB, England. Pergamon-Elsevier Science Ltd. 503-510.

Abstract: Immediate and delayed recognition memory for words was examined in a sample of 16 non-demented patients with Parkinson's disease and 16 normal control participants of equivalent age and educational attainment. The patients, relative to control participants, had intact immediate but impaired delayed recognition memory performance. Patients were also impaired on tests of free and cued recall, working memory and a measure of psychomotor processing speed. Processing speed was a significant covariate for delayed recognition, free and cued recall and working memory performance, but not for, immediate recognition performance. These results suggest that the same cognitive processes which support performance on tests of recall and working memory also support performance on tests of delayed recognition.

Note: Article Stebbins GT, Rush Med Coll, Dept Neurol Sci, Suite 450, 1645 W Jackson, Chicago,IL 60612 USA

Keyword(s): cognition and basal ganglia; fronto-striatal memory system; FRONTAL-LOBE DYSFUNCTION; PREFRONTAL CORTEX; COGNITIVE DEFICITS; DOPAMINE; AGE; INVOLVEMENT; IMPAIRMENTS; TOMOGRAPHY; RECEPTORS; LESIONS

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