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May 2024

Pharmacologic treatments for drug and alcohol dependence

Author(s): Amin, H., ModestoLowe, V., Oncken, C.

Journal/Book: Psychiat Clin N Amer. 1999; 22: Independence Square West Curtis Center, Ste 300, Philadelphia, PA 19106-3399, USA. W B Saunders Co. 401+.

Abstract: Although psychosocial methods remain the most widely used approach for the treatment of patients with substance-use disorders, pharmacotherapy has come to play an increasing role in such treatment. Individual and group counseling and 12-step programs are basic elements of most rehabilitation programs for alcohol and drug dependence. Although medications are commonly used to treat withdrawal from alcohol, sedatives, opioids, or nicotine, their role in the rehabilitation of patients dependent on these substances remains limited. Notable exceptions to this include opioid-agonist maintenance and medications used to treat comorbid psychiatric disorders in patients with a substance-used disorder. This article focuses on medications that serve to augment psychosocial therapies in the rehabilitative treatment of patients with opioid, nicotine, alcohol, and cocaine dependence.

Note: Article Kranzler HR, Univ Connecticut, Ctr Hlth, Dept Psychiat, Sch Med, 263 Farmington Ave, MC2103, Farmington,CT 06030 USA

Keyword(s): COCAINE ABUSE; SMOKING CESSATION; DOUBLE-BLIND; CONTROLLED TRIAL; PHARMACOTHERAPY; NALTREXONE; THERAPY; DISULFIRAM; PLACEBO; PSYCHOTHERAPY


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