Zhongguo Zhong Yao Za Zhi. 1998 Nov; 23(11): 695-8, inside back cover.

[Clinical effect of tianma-cuzhi granules on senile vascular dementia]

Du G, Chen K, Zhou W, Zhao Y, Wang X, Cui H, Zhu X, Liu X.

Institute of Chinese Materia Medicine, China Academy of Traditional Chinese Medicine, Beijing 100700.

OBJECTIVE: To assess the clinical efficacy of Tianma-cuzhi Granules (TMC) in treating senile vascular dementia(VaD) of the "sthenia of liver-yang" type. METHOD: TMC were given to thirty VaD patients three times a day of 0.5 g/bageach. The treatment course was one month and the patients finished two consecutive courses. RESULTS: TMC could markedly increase the mini-mental state examination (MMSE) and Hamilton depression scale(HDS) marks of VaD patients, and also contribute to improving certain indexes especially in abnormal cases. CONCLUSION: TMC have certain effects on senile VaD.