Effects of Ginkgo biloba extract on cognitive function and blood pressure in elderly subjects

Author(s): Winther, K., Randlov, C. , Rein, E. , Mehlsen, J.

Journal/Book: Curr Ther Res Clin Exp. 1998; 59(12): 881-888.

Abstract: In this randomized, double-masked study, we assessed the effects of a Ginkgo biloba (GB-8) extract on elderly volunteers with age-related cognitive dysfunction. A total of 260 subjects were tested to obtain a homogeneous group of 60 elderly subjects with mild-to-moderate cognitive impairment, as defined by a clinical rating scale. The subjects were allocated to one of three groups and received either GB-8 40 mg or 80 mg or placebo three times daily for 3 months. Before therapy was started and after 1 and 3 months of treatment, standardized testing of attention, concentration, and memory was performed. The subjects completed self-assessments before and after 3 months of therapy, and vement appeared to be clinically relevant. The possible antihypertensive action of Ginkgo biloba extract is sufficient to warrant further investigation.

Keyword(s): phyto. cr. ginkgo.

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