The neurobiology of attention-deficit/hyperactivity disorder

Author(s): Liotta, W.

Journal/Book: J Clin Psychiat. 1998; 59: P O Box 240008, Memphis, TN 38124. Physicians Postgraduate Press. 17-23.

Abstract: We provide a comprehensive review of the neurobiological basis of attention-deficit/hyperactivity disorder. This summary was accomplished by a review of research in three areas: neuroimaging, genetics, and neurochemistry. Additionally, we also discuss a newer conceptualization of the disorder. Although none of the current findings present a unified picture of the pathophysiology of the disorder, the vast array of studies reviewed do highlight CNS abnormalities that, when taken together, present a convincing argument that the cause clearly resides within the realm of developing brain.

Note: Article Zametkin AJ, NIMH, Bethesda,MD 20892 USA

Keyword(s): DEFICIT-HYPERACTIVITY DISORDER; CEREBRAL GLUCOSE-METABOLISM; QUANTITATIVE MORPHOLOGY; DOPAMINE TRANSPORTER; BRAIN METABOLISM; CORPUS-CALLOSUM; CAUDATE-NUCLEUS; THYROID-HORMONE; ADULTS; CHILDREN

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