Natural history of Alzheimer's disease and other dementias: Review of the literature in the light of the findings from the Kungsholmen Project

Author(s): Fratiglioni, L., Winblad, B.

Journal/Book: Int J Geriat Psychiat. 1998; 13: Baffins Lane, Chichester, W Sussex PO19 1UD, England. John Wiley & Sons Ltd. 755-766.

Abstract: The elderly population is increasing more than any other sector of the population. Dementia, a prevalent condition in the elderly, increases disability, morbidity and mortality among older people. For these reasons the possibility of predicting progression and prognosis has enormous importance. Despite the fact that dementia has gained widespread recognition in the past few decades, the knowledge of its natural history, in terms of progression and prognosis are not yet completely understood. However, thanks to longitudinal research, which has only recently begun to proliferate, not only is better comprehension of the continuity of the cognitive decline possible, but also the identification of some prognostic factors.

Note: Article AgueroTorres H, Stockholm Gerontol Res Ctr, Kungsholmen Project, Box 6401, S-11382 Stockholm, SWEDEN

Keyword(s): dementia; Alzheimer's disease; natural history; progression; prognosis; LONG-TERM-CARE; MULTI-INFARCT DEMENTIA; 3-YEAR FOLLOW-UP; COGNITIVE IMPAIRMENT; FUNCTIONAL DECLINE; VASCULAR DEMENTIA; NURSING-HOME; EXTRAPYRAMIDAL SIGNS; MIXED DEMENTIA; INCREASED RISK

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