The physical basis of neuroimaging techniques

Author(s): Gore, J. C.

Journal/Book: Child Adolesc Psychiatr Clin. 1997; 6: Independence Square West, Curtis Center, Ste 300, Philadelphia, PA 19106-3399. W B Saunders Co. 213.

Abstract: The physical concepts behind the most important neuroimaging techniques in use today are described, along with the different types of information that can be obtained by different methods. Technical aspects of MR imaging, nuclear imaging (including both single-photon emission computed tomography as well as positron emission tomography), and X-ray imaging methods, as used for the study of brain structure and function, are described. The relative advantages and disadvantages of different types of imaging are evaluated, along with the fundamental and practical limitations that are placed on the quality of images and information provided by each method. Particular attention is paid to the variety of measures of structure, function, and tissue characteristics available from MR imaging, because these are of particular importance in the study of pediatric populations. Finally, some future trends in the relative importance of different methods are estimated.

Note: Article Anderson AW, Yale Univ, Sch Med, Dept Diagnost Radiol, New Haven,CT 06520 USA

Keyword(s): FUNCTIONAL MRI; TOMOGRAPHY; RECEPTORS; BRAIN

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