Cytostatic activity against HEp-2 cells of methanol extracts from VISCUM CRUCIATUM Sieber parasitic on CRATAEGUS MONOGYNA Jacq. and two isolated principles

Journal/Book: Phytother-Res. 11 (3), 240-242. 1997;

Abstract: We have determined the cytostatic activity in vitro against HEp-2 cellsof methanol extracts from V. cruciatum Sieber (Viscaceae) parasitic onC. monogyna Jacq. (Rosaceae), C. monogyna parasitized and C. monogyna,non-parasitized. The methanol extracts assayed exhibited a moderatedegree of growth inhibition compared with the values obtained with the6-mercaptopurine (solution used as a positive control). Hyperoside fromC. monogyna showed only a low degree of growth inhibition. However,beta-amyrin acetate, from V. cruciatum, exhibited a high degree ofgrowth inhibition compared with the values obtained with the solutionused as a positive control.COPYRIGHT BY Elsevier Science BV, Amsterdam, Netherlands END OF DOCUMENT

Keyword(s): Medical:cytostasis

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