Origin of premenstrual syndrome: assessment by endometrial ablation.

Journal/Book: J-Am-Assoc-Gynecol-Laparosc 1994 May, VOL: 1 (3), P: 207-12, ISSN:1074-3804.. 1997;

Abstract: STUDY OBJECTIVE: To determine the origin of premenstrual syndrome (PMS)by endometrial ablation. DESIGN: Evaluation of 108 consecutive womenrequiring endometrial ablation. SETTING: The study was conducted inseveral hospitals and a surgical center in Fort Worth, Texas. Evaluationof patients was done in-office. PATIENTS: The women had disablinguterine bleeding not related to malignancy. Of the 108 women, 6 werehaving a second procedure. INTERVENTIONS: All women underwentendometrial ablation with the rollerbar resectoscope under localstand-by anesthesia, with suction curettage preparation of the uterus.MEASUREMENTS AND MAIN RESULTS: The 73 women who were identified with PMSwere evaluated by a 12-point protocol preoperatively and between 1 and 2years postoperatively to gain insight into the origin of PMS. Aftersurgery most of them were initially amenorrheic and essentially free ofsymptoms; however, with recurrence of bleeding PMS often recurred.Persistence of amenorrhea after ablation was associated with continuedrelief of PMS. CONCLUSIONS: We postulate that the etiology of PMS inwomen with disabling menstrual bleeding involves products from orsubstances in endometrial tissue. Author.

Keyword(s): ADULT

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