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May 2024

Electrophysiology in the locked-in-syndrome

Author(s): Isenmann, S., Wichmann, W.

Journal/Book: Neurology. 1996; 46: 34 Beacon Street, Boston, MA 02108-1493. Little Brown Co. 1092-1101.

Abstract: We investigated five patients with a locked-in-syndrome (LIS) and reported the clinical, electrophysiologic, neuroradiologic, and neuropathologic findings. EEG reactivity was present in two and absent in three cases. Somatosensory evoked potentials (SEP) varied from unilaterally normal to bilaterally absent. We conclude that there is no specific pattern of SEP abnormality characteristic of LIS and that EEG reactivity cannot be taken as a sole measure of consciousness.

Note: Article E Gutling, Univ Zurich Hosp, Dept Neurol, EEG Unit, CH-8091 Zurich, Switzerland

Keyword(s): SOMATOSENSORY-EVOKED-POTENTIALS; SEVERE HEAD-INJURY; BRAIN-STEM; STATE; INFARCTS; DAMAGE


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