Indian J Exp Biol. 1995 Oct; 33(10): 798-800.

Effect of D-400, a herbomineral preparation on lipid profile, glycated haemoglobin and glucose tolerance in streptozotocin induced diabetes in rats.

Mitra SK, Gopumadhavan S, Muralidhar TS, Anturlikar SD, Sujatha MB.

R&D Centre, Himalaya Drug Co., Makali, Bangalore.

This study was undertaken to investigate D-400, a herbomineral formulation in streptozotocin induced diabetes in rats. Glycated haemoglobin, lipid profile and glucose tolerance test were studied. D-400 has an established hypoglycaemic effect in alloxan induced diabetes in rats as well as in non-insulin dependent diabetes mellitus patients. D-400 treated group showed lower glycated haemoglobin, triglycerides and higher HDL levels. The hyperglycaemic response was blunted after administration of oral glucose in the same group.