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May 2024

The Landau-Kleffner syndrome: A review

Journal/Book: Eur Child Adolesc Psychiatr. 1995; 4: PO Box 2487, Kirkland, WA 98083-2487. Hogrefe & Huber Publishers. 223-228.

Abstract: The Landau-Kleffner syndrome or the syndrome of acquired epileptic aphasia was first described in 1957. The disorder is characterised by gradual or rapid loss of language in a previously normal child. All children have abnormal EEG compatible with the diagnosis of epilepsy, however, only 70% have clinical seizures. The present article presents a review of the current knowledge concerning this disorder. Information is provided related to the clinical picture, etiology, pathogenesis, treatment and outcome.

Note: Review SE Mouridsen, Bispebjerg Hosp, Dept Child Psychiat, DK-2400 Copenhagen, Denmark

Keyword(s): Landau-Kleffner syndrome; epilepsy; aphasia; ACQUIRED EPILEPTIC APHASIA; VERBAL AUDITORY AGNOSIA; CONVULSIVE DISORDER; FOLLOW-UP; CHILDREN; CHILDHOOD; EEG; LANGUAGE; ONSET; PSYCHIATRY


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