Magnetic field tomography of cortical and deep processes: Examples of ''real-time mapping'' of averaged and single trial MEG signals

Author(s): Liu, M. J., Liu, L. C., Bamidis, P. D., Hellstrand, E., Stephan, K. M.

Journal/Book: Int J Psychophysiol. 1995; 20: PO Box 211, 1000 AE Amsterdam, Netherlands. Elsevier Science Publishers BV. 161-175.

Abstract: Magnetic field tomography (MFT) provides 3-dimensional estimates of brain activity, from non-contact, non-invasive measurements of the magnetic field generated by coherent electrical activity in the brain. MFT analysis of averaged auditory ''odd-ball'' data show cortical and deep activation, presumably from the amygdala and hippocampus. These results are compared with MFT estimates obtained from a patient who had undergone lobectomy which removed these structures. The variability from subject to subject is confounded by variability between trials for the same subject; the relationship between the averaged and single trials is probed by bi-hemispheric simultaneous measurements performed under the same odd-ball paradigm and by MFT analysis of auditory evoked data and interictal epileptic activity.

Note: Article AA Ioannides, Open Univ, Dept Phys, Milton Keynes MK7 6AA, Bucks, England

Keyword(s): functional brain imaging; evoked potential; MEG; magnetic field tomography; amygdala; hippocampus; auditory odd-ball; interictal epileptic activity; single trial analysis; BIOMAGNETIC INVERSE PROBLEM; AUDITORY EVOKED-POTENTIALS; MIDDLE-LATENCY; ENDOGENOUS POTENTIALS; HIPPOCAMPAL-FORMATION; HUMAN BRAIN; LOCALIZATION; LESIONS; MAGNETOENCEPHALOGRAPHY; EEG

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