The neuropathology of Parkinsonism: An overview

Author(s): Chang, L., Miller, B. L.

Journal/Book: Brain Cognition. 1995; 28: 525B Street, Suite 1900, San Diego, CA 92101-4495. Academic Press Inc Jnl-Comp Subscriptions. 321-341.

Abstract: The neuropathology of parkinsonism is reviewed as it occurs in primary (idiopathic) and secondary extrapyramidal syndromes. Present understanding of the significance of Lewy bodies in Parkinson's disease, diffuse Lewy body disease, and Lewy body variant of Alzheimer's disease is emphasized. The neuropathology produced by a variety of secondary causes is also considered to demonstrate the diverse lesions that can result in parkinsonism.

Note: Article ME Cornford, Univ Calif Los Angeles, Med Ctr, Dept Pathol, 1000 W Carson St, Torrance, CA 90509 USA

Keyword(s): LEWY BODY DISEASE; ELECTRON-MICROSCOPIC IMMUNOCYTOCHEMISTRY; SUPRANUCLEAR GAZE PALSY; ALZHEIMERS-DISEASE; NEURODEGENERATIVE DISEASES; CLINICAL-DIAGNOSIS; SPHEROID BODIES; GLOBUS-PALLIDUS; SENILE DEMENTIA; HORN CELLS

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