J Ethnopharmacol. 1991 Jul; 33(3): 289-92.

Traditional medicinal plants of Thailand. XVII. Biologically active constituents of Plumeria rubra.

Hamburger MO, Cordell GA, Ruangrungsi N.

Program for Collaborative Research in the Pharmaceutical Sciences, College of Pharmacy, University of Illinois, Chicago 60612.

The compounds 1-6 were isolated from the heartwood of Plumeria rubra, following bioactivity-directed fractionation. Plumericin 1 and isoplumericin 2 displayed molluscicidal, cytotoxic and antibacterial activity, 4-hydroxyacetophenone 3 was weakly cytotoxic, whereas the remaining glycosidic isolates (plumieride, 4; 13-O-coumaroylplumieride, 5; protoplumericine A, 6) were inactive in all test systems.