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May 2024

Immunologisch aktive Inhaltsstoffe eines standardisierten pflanzlichen Immunmodulators- Information zur Analytik und Wirkung -

Abstract: As could be demonstrated by means of a constant correlation between chemical analytics and biological activity polymeric components play an important role with regard to the immune modulating action of an immune modulator of plant origin.In the case of Thuja occidentalis, polysaccharides have to be mentioned, which also are provided by both Echinacea purpurea and Baptisia tinctoria, besides glycoproteins (arabinogalactan proteins). Particularly the structures and grades of branching of high-molecular components are decisive for the immunological activity.The immunological method (ELISA) developed especially for chemical standardisation allows a quantitative determination of active substances, which are used in various biological test systems. Thus, the preparation investigated may be standardised using glycoproteins and arabinogalactan proteins, respectively. The standardisation on immunologically active components is especially important with regard to a uniform efficacy of individual batches.

Keyword(s): Immunmodulation


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