Hua Xi Yi Ke Da Xue Xue Bao. 1990 Mar; 21(1): 46-9.

[Investigation on role of nucleus parabrachialis medialis in "renzhong" induced respiratory response in rabbits]

Chen Z, Qing D, Zheng Y.

Experiments were performed on 27 rabbits, bivagotomized, gallamine triethiodide immobilized and artificially ventilated. The effects of electric stimulation of "Renzhong" (Du26) area, NPBM separately, and "Renzhong" area and nucleus parabrachialis medialis (NPBM) simultaneously, on phrenic nerve discharge were observed before and after electolytic and chemical lesion of NPBM. Evoked potential (EP) could be recorded in NPBM during the electric stimulation "Renzhong" area. Electric stimulation of the same site of NPBM where the EP was recorded could induce respiratory response and change the effect of electric stimulation of "Renzhong" area on respiration. But after electrolytic and chemical lesion of NPBM, stimulation of NPBM could no longer induce the respiratory response mentioned above and could not change the "Renzhong" effect on respiration either. These results suggest that NPBM might take part in respiratory effects of "Renzhong" area stimulation, but is not essential to it.