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May 2024

Extracellular Matrix and Holistic Medicine

Journal/Book: Natur- und Ganzheitsmedizin Wissenschaft und Praxis. 1990; 3/3: 68-72.

Abstract: Holistic medicine means efforts towards an individualistic medicine. The basis of each individual life are biological rhythms. The main rhythm seems to be the circadian rhythm of the groundsubstance (extracellular matrixl. It synchronizes all the diverse cellular rhythms of the body. A crucial role in the basic rhythm plays the grade of sulfation of proteoglycans and glycosaminoglycans (PG/ GAGsI. The maximum of sulfation of the groundsubstance during the night is paralleled with a maximum of water-, electrolyte- and protein binding capacity. This turns to a minimum in the morning. Phagocytes, cortisol and adrenalin have an inverse rhythm. The findings presented show that the PG/GAGS in the blood plasm of patients with chronic diseases and tumors are diminished and composited in a different way. It is discussed whether exogenous caused pathologic rhythms of the groundsubstance catalyze these diseases.

Keyword(s): Grundregulation


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