Pharmacology. 1988 ; 36 Suppl 1(): 126-8.

Metabolism of sennosides--an overview.

Lemli J.

Laboratory for Pharmaceutical Biology and Phytopharmacology, K.U. Leuven, Belgium.

The metabolism of sennosides is discussed in view of the results obtained during the last years. Rhein anthrone is to be considered as the ultimate active form produced by microorganisms in the colon. Several contributions of this senna symposium bring complementary information of utmost interest.