chemotaxin fMLP

Author(s): Fletcher, M. P., Halpern, G. M.

Journal/Book: Proc GIRI. 1988; 2: 18.

Abstract: Hypaque-Ficoll purified (95%) PMN from normal subjects were assessed for FMLP-elicited (DY) responses, intracellular hydrogen peroxide production and phagocytic activity using flow cytometry and appropriate fluorescent probes. Superoxide (O2tion of isolated cells was measured spectrophotometrically as the superoxidc dismutase-inhibitable reduction of cytochrome C. The modulatory effects of dilute solutions of the arachidonic acid derived lipid inflammatory mediators c for LTB4 and PGE1.

Keyword(s): hom. rel. exp. hum. low dose.

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