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April 2024

Antibacterial activity of Euphorbia thymifolia Linn

Author(s): Rahmann, M., Nur-e-Kamal, M.

Journal/Book: Indian Journal of Medical Researche. 1988; 87: 395-397.

Abstract: E. thymifolia Linn. was extracted with rectified spirit, and the extract partitioned between petroleum ether, chloroform, ethylacetate and water. In vitro test of these fractions, showed that 450 ?g/ml of ethyl acetate extract and 750 ?g of chloroform extract could inhibit the growth of the Escherichia coli and Shigella flexneri. Ethyl acetate extract appeared to be more potent than the chloroform extract. The ethyl acetate extract was found to be active against Sh. flexneri in vivo. It was observed that 1500ug of the ethyl acetate extract per day could cure 80 per cent of the infected mice.


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